Nguyen TK Thanh Mae

Nguyen TK Thanh Mae

Professor
University College London (United Kingdom)

Prof. Thanh held a University Research Fellowship (2005-2014) and Professor of Nanomaterials at the UCL Healthcare Biomagnetic and Nanomaterials Laboratories and Department of Physics & Astronomy, University College London. In 1992, she received the award for top academic achievement in Chemistry at Vietnam National University in Hanoi and was selected to study at the University of Amsterdam under a NUFFIC (the Netherlands organization for international cooperation in higher education) program, which marked the start of her research career. In 1994, she was selected for an EUfunded PhD position in Biochemistry. She developed a method to analyze different types of lipids in rat kidney...

Nanomaterials for the Future

The strategic engineering of advanced nanomaterials is a cornerstone of next-generation healthcare technologies. Among these, plasmonic and magnetic nanomaterials have emerged as powerful platforms because of their unique optical, electronic, and magnetic behaviors at the nanoscale. By combining these properties, researchers can design smart, multifunctional systems that bridge the gap between diagnosis and therapy (theranostics). This innovative research leverages the synergistic effects of noble metals and magnetic oxides to overcome the limitations of conventional medicine, offering highly precise, minimally invasive solutions for early disease detection and targeted cancer treatments. The four pillars of the research framework are:
1. Design: Conceptualizing complex hybrid architectures (such as core-shell, heterodimers, or branched structures) to maximize synergy between magnetic and plasmonic fields while ensuring longterm colloidal stability.
2. Synthesis: Utilizing advanced chemical routes (including thermal decomposition, co-precipitation, and microfluidic synthesis) to achieve rigorous, reproducible control over the size, shape, and crystallinity of the nanoparticles.
3. Characterization: Employing state-of-the-art analytical tools—such as Transmission Electron Microscopy (TEM), X-ray Diffraction (XRD), and SQUID magnetometry—to assess physical metrics and validate precise structure-property relationships.
4. Biofunctionalization: Engineering the nanoparticle surface with biocompatible polymers (e.g., PEG) and specific targeting ligands (antibodies, peptides, or aptamers) to evade immune clearance andselectively bind to molecular biomarkers.
The lecture will cover examples and applications of magnetic and metallic nanoparticles.